148 HPV, HIV, and Cancer

HPV seroconversion following anal and penile HPV infection in HIV-negative and HIV-infected MSM.

BACKGROUND We assessed human papillomavirus (HPV) seroconversion following anal and penile HPV infection in HIV-negative and HIV-infected men who have sex with men (MSM). METHODS MSM aged ≥18 years were recruited in Amsterdam, the Netherlands (2010-2011), and followed up semiannually. Antibodies against 7 high-risk HPV types in baseline and 12-month serum samples were tested using a multiplex...

[HPV and cancer].

HPV infections and oesophageal cancer.

The first reports suggesting an involvement of human papillomavirus (HPV) in the development of both benign and malignant squamous cell tumours of the oesophagus date back to 1982. Since then, a substantial amount of literature has accumulated on this subject, summarised in this review. To date, 239 oesophageal squamous cell papillomas have been analysed in 29 separate studies using different H...

HPV vaccines and cervical cancer.

Human papillomavirus (HPV) vaccines have opened a new perspective on the prevention of cervical cancer, one of the most paradigmatic long-term goals of the cancer prevention field. For decades, prevention has been and still is partially fulfilled by the expansion of the practice of cervical cytology (the Pap smear) repeated frequently in tens of millions of asymptomatic women worldwide. The pra...

HPV infections and lung cancer.

Because of the major clinical impact of bronchial cancer worldwide, the possibility that human papillomavirus (HPV) contributes to its pathogenesis as a co-carcinogen is an intriguing one. Bronchial squamous cell carcinoma develops through well defined precursor lesions, often at the sites of squamous metaplasia. Benign squamous cell papillomas are rare but HPV DNA has been found in almost half...